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Clinical Reference Systems: Pediatric Advisor 10.0

Drug Rashes

DESCRIPTION

Most rashes that are caused by an allergic reaction to a drug appear as hives or are very itchy. Hives are raised pink spots with white centers. Their size, shape, and location change frequently. Some less common rashes caused by drug allergies are widespread red patches or target- shaped rashes.

Usually a rash that develops while a child is taking a medication is caused by a virus and is unrelated to the medicine. Examples of viral illnesses that cause rashes (viral exanthems) are roseola, measles, and many summertime viruses that also cause diarrhea.

Another kind of rash may occur when a child is taking amoxicillin or ampicillin. It is called a toxic rash. It consists of small pink spots, mainly on the chest, abdomen, and back. The rash is not caused by an allergic reaction to the medicine. A child who has such a rash can continue taking the medicine.

(For more information see Ampicillin Rash. )

HOME CARE

  1. Stopping the medication

    If your child is diagnosed as being allergic to a medicine, he can never take any drugs in that drug category again. (For example, if he is allergic to one type of penicillin, he cannot take any of the penicillin drugs.) Hence, this is a critical decision. Unless your physician tells you otherwise, have your child examined before you stop a medication. However, there are a few exceptions. Stop the drug if:

    • Your child has a severe rash AND is taking antiseizure or sulfa drugs.
    • You are certain your child has hives.

  2. Replacing the antibiotic

    Anytime antibiotics are discontinued before a child has completed the full treatment, a doctor should see the child within 24 hours to determine whether he or she needs a new antibiotic. Without this precaution, many children will have flare-ups of partially treated infections.

CALL YOUR CHILD'S PHYSICIAN IMMEDIATELY IF:

  • Your child has hives or is very itchy.
  • The rash is severe.
  • The rash is purple or blood-colored spots or dots.
  • Your child is acting very sick.

CALL YOUR CHILD'S PHYSICIAN WITHIN 24 HOURS ABOUT:

  • All children with mild widespread rashes that occur while they are taking a medicine.

Note: A rash caused by an allergic reaction appears on most of the body. A rash that affects just one part of the body is not caused by drugs.

(See Rashes, Localized Pink or Red. )


Written by B.D. Schmitt, M.D., author of "Your Child's Health," Bantam Books.
Copyright 1999 Clinical Reference Systems